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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b05f568b0e32af37b0f18c920cdad7c0015fb97b38bb4f3ae6043152575c4ee5' 
  AND token = 'QEPBNaj80uT57K+XVS6HJeiXxFnKXSiSqGjY1oV2bU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}