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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'da1c3524a1f99092eca816f9b99d9157de94eea3b94ea0c0f7281ff617f1154a' 
  AND token = '5Nbv2b+emk6WvB6fBK9AqMUx+LFAjO5QnTFLrnreeNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}