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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '499f107bb527922a4dcfda10dc2182a0248120a7a07d93b77b9bcc9201c0aa37' 
  AND token = 'VJJ0U3IzLVFYdiSo9AHbB3j0QlHOb2mABvPs31/L2zw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}