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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5ca93cea49f73314e9733cf14fe4836ca6ea3d6c98d56264c1aae3a03c591bb9' 
  AND token = 'IM0CEC+HvSyapMtvO5xyfb+lur2WairADJKTUHRkGhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}