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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0a50581ca3b46188cf89e5d73ab3c5c46318f8bef445b133070b3e90994f74fc' 
  AND token = 'c6QNeg1MC1syI4v1R+66AAbhxK6VwtWtsQp9vNYLToU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}