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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f39e5d6c3a7e54efe40098d9db45aadd202abdcb0378a470a58f259a6c20d92b' 
  AND token = 'zdyr2SFmZgHkjgu2tjpa9dfVHo05gE4y9gXMGJAE7Z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}