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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5cde300425922d9d10a23c198486a97f9cfac10a7a8dc0478bed4174d7f19775' 
  AND token = '/8wfpOvbfxzqnTt2t0V3U72gk07IKEEB3q39eH27gxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}