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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f1f8dfd44f95df235f037988d399c00caad73124b4f527c8653dde396b834ae8' 
  AND token = '7bOwQMXruyrttEVXGd+qb/nkk6/YAiMCLklnKeiwSKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}