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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '53debcd3d279de3120610370a4db8846b58d4e500df3c86a431e17e86dbcf4fd' 
  AND token = 'VOtA+EBop0wiy/KrlaF39pa4zSDvan3uOZgB3HUIX5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}