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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '29d597ab3df35363166b26d3d4a22f0cc9da3a055241c99d755e8c08eef4c836' 
  AND token = '/0soFDrX1Qmb91g2cphx4WfxaUdNcuyslp81h5CGE1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}