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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2d1d25217d6db2e002bbdf2c8ed2dd8a84d6b983017c6f6c827c1a80a9765d54' 
  AND token = 'RKNWxrdjzfDfaKG0SZN3eGoH3GGqGD2De1V6y7CNSqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}