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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '51e0ff1cae0ba22bc5d712c043a2e681e55eb9f2178fc80dcb77d09e07f1e9b7' 
  AND token = '9XN469xZ2Z77kIToQyWNczOjByPZi6C4gcya5eQC3kQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}