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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'bb9d0e4b49e8efaa337afc73be6385560610dd1c7615f4d7e6f2219280514850' 
  AND token = 'oVReLsRVK6mSIIg+TDlVXI/V7LR8rSxgNPAF0N9CYFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}