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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c1e89636192db972660fe55dfca128e6d7e0dc1f2ce928d8d40ed9007b4e3165' 
  AND token = '2WZpPgwMBMoGJ7kNZfMMdMg4QRvjorFOmZAtxV6cQG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}