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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '33cb306aace5c10bba4cdfcc64ec810a097ee972c5c6d2715664f0398d9685c1' 
  AND token = 'T90Zr2WjsNEEnTSUEW/GJaPh5+Hy0UFd4XPrXK2g0qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}