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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b4667421aa284577df02255c64da3b2014b66a98221129272e94e56196270f55' 
  AND token = 'q7Wc79GfkxIoK3/stbk3fyoVTygLOCVdhnOaW3HXaHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}