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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '116561d87158becf02dd6834a63b73a0d290157cf3ec7a0438883b1e8a160893' 
  AND token = 'bd9PWdk7xvFHSTkcN/ko4tmOFT4N06VqEtOtsoMhpQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}