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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1d6ce98f8de5f23fbd7ff9837c2a677d29abef62493cc6bcee8df890951e3b99' 
  AND token = 'cvrp/ArZVg9I8oD1mXIqfm9Fx2X9YZfKbk1RLkoD0eU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}