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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b1eb0badaa96ccfe26353279bff9b887b7cb29aedfe04f358bbc8db745c282f6' 
  AND token = 'lhQxGLArIsXn6K38wiwxaZenfnHhDxLH4Hz6365WsHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}