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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '644f94c4c6c6b9159b9851828e9cef7335cec6ebd3ea69405546c030a6814364' 
  AND token = 'wCJcq7qR208jcSKcewY0vgrNFXqRM1d7b3xbWy6Ti3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}