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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ad3e6c7ce2d89460d530bdefc024b068c09b3557dce0e8293f2a209944835449' 
  AND token = '19Y8s1IKC6X6LVBD1wkMIHV/2kGZ57d8bXbHaOkmfOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}