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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2bde18551bdaa13591bfc24051bef6520513c77621b9e5a73fc3f3e5459d7721' 
  AND token = 'XPDrBpn7XwFHoHlP0IosnnAW5aTd2g4LV3gjJBRrWiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}