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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a4fff54467732cb2f07e9f41b2191aaf14388806bfc76878a5b4e353663de433' 
  AND token = 'FpDr1y2M2f0/SW7Uf780TGzM2XnoR0Rwg4QXNj9YuxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}