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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd138295df8f0c6bb80b63449ce637e2ac7990ba78051a5f8e0bdb75f99bff4f6' 
  AND token = '3G65+wDF1UWZNLWWHRZZnH51yKGfXnbpNirmaxBmHyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}