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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22d7c66c9eee31f3b2a4352dd17af1853520f46112061a03703cddacc9905f31' 
  AND token = 'PFeC9yh1d34QnSRHWFHTrneo4BKGFuHJMZAmxaATddE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}