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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c81896f91859693ed906485082a205fbb4520a9727e5ac39584eab7e8726a7f9' 
  AND token = 'IyKzuLVeSR45/BVJ8wOKMzDrF00oHm8s3e8Ao8SdPhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}