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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2b7d5fdf9f2ee52ba5e9aceeb490992bb8aec7d1db1c5338f127fc739a8cfda5' 
  AND token = 'ydc4iTSQeqZtsoAmX++aFRG3UP3PdfZ1AOQmxunA0zI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}