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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e888084a4a3c3f92687ef6b4f34f940f427bc95056d653c8d7cab603ce364167' 
  AND token = 'QqQficIBD264RiBD5zr10W+pCt1vn+JloTI+mQlBOUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}