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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '896c31fa2ae75bc1f64a466beecb0553f878295a4ce782e7211f8f3e8b4fe63b' 
  AND token = 'YGiTq+7aY6OdhyHVr5aqNAz3UbWRSiFUL/IXc6dL24k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}