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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4e6091967f1b57a711da965ede717f730110cb00661d685a9efbc5bd6522ddd1' 
  AND token = '0qTOk1AnhHBQqlJndBWfkHYIxbCs3GfRZOVmMmDihQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}