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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ec12dbe57795021b7fa8a0d1ee65b64416436eff0719afd0eb4bc6e646078a25' 
  AND token = '+sJpAY8iNN04G7Y/izKk0t7XrzS7hebbhTn1y8Ed+sU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}