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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3e7ca279d9f67ab65b147c8f80eaff1a5edea53586f113922b635f7bbcdf3778' 
  AND token = '2340yqfTZJnTP/eMlXERiK13XDPu0zPsZDP/FXM9CmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}