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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '857eee40fed43a5e639b5f1c46a28849f92f07603a111e116c66434b6ff3f2b8' 
  AND token = '13qpNYNdQxD2JWMTMy72MAivj3VSOlh8CgygrCjkJsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}