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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e079a7be7bdda46d283b27a960c3df7811b9d99a437b9be85dc4f3db459f120b' 
  AND token = 'DrV2FYijWE0bsbr81GXJjdOLv0MnZQwEIywNWuGE8SM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}