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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd2152d760529e8a026cf32abd3a009d7b796c0a86617c4469c3e1a31be250576' 
  AND token = 'UMMskBHQJEP+sX9RpREylu1WJDLv9wUGfaI9T2yEUZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}