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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a2902294a03e593309e4639647a9b19cd48a32f14e73812a035687cb4f100302' 
  AND token = '9efGWFjQHAd15qbDsvqsAFWztJuJHNof0fvEW9xYYXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}