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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0ca3031bca51e23930a6bf442792e013f7bafa310c0364d32f122f1a45127f21' 
  AND token = '0e8MW1bFskFG0N1plRYMZ8WkN/Ifs9S5CSrN6lt7LiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}