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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '247f32412f1cff27ad96e91bb060dcaac476b7d76c2776a01ac023f3df0df160' 
  AND token = 'qh2oHFJpMziOlvMSSzZaiNS1u8AFh5x6WS+VCH9w2zw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}