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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3901f372e5cc68f656524102e88c079a48fb0bd6aaea9e8c3050e7b32cd01518' 
  AND token = '/VMjxScwN2xK5ejCzV9saI0/9MeaFZgVASjonniAotg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}