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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1c75eb53f6ed75b120c746738d8a84e7c909594aace420c14214237c5ce505b5' 
  AND token = 'N9yj90Xhuv4Ug7WlO0K1bxYtBFl67tiR/vfE9e0d/6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}