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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1751023fa8776956a276b5d2a822e75870bc57bbedd9031d7b548ed7054b654f' 
  AND token = '02+LUVWo5HY7QWI21c2xTTLXzvLDGT1mexqfUCsqWwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}