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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2bef88ae7eeb12662be5a032b84b1dc86e3aa1b87adf3f344b077b8f40144449' 
  AND token = '43rz//4Ppxo0crPMRkVTXiaAJiZtvUx+BOl/qvrWr4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}