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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '045724d34df70696a2476e08aabf289129cedc6af07edfd9e3ecb5d320613999' 
  AND token = 'PcIXkvP02vTGa0uA6VbBSt+tpogiWTyMBktoxsYHlHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}