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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e10b8fa40944f84e19abf40a321f7cab2425682e64b170aac25781a95314a58e' 
  AND token = 'nlcxmmPnfRV7oe3Y0gZbTy/xUtHuPstXzCQAhcCIdVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}