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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cf221f4db7a6ea1c9265ff3c95e4ff406ab07be9a8084bc693133258a399e0e6' 
  AND token = 'XMJWOAxZUT4XBfAoQb9Wzq4woFwYLo85neGYFNY30PY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}