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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f749d259cb483de6a70394443329ab375905a06efdd52e4f4d73fde04445e4cc' 
  AND token = 'tEGT3Akoob45/K4Wmi3f2+lL99RKkgReamkDUooVm90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}