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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b625868fda55c181360a75955ffcdc173c6e85b939785d98dfa51ecd91b3f9ff' 
  AND token = 'UZQG23n787ygb5+cGBauB36sCyEZQRPX4+QuI+5NvGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}