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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b42ba209410fdfceab5bde96adc3299c52204e8fca51e31b8894208b19f2d022' 
  AND token = '330aBFP8i3z6s8vt6AuhV7k1FxMnzoiIw5kjZttp3WA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}