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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9fa50f2f192958df080dd6113b00a8413d904564fab1cdeec9e0c7e280015211' 
  AND token = 'JC36q+wHq6Wwx7gWvk8KYF+5crK6oT9+DW4cfcKXhkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}