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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4deeea62d6a3414f1810aba848f8f819a9a13dfe4c7c0aade6bca624b349d832' 
  AND token = 'R1Bwa5TIicgcPUBpqbs502Dz5hyuWK8CtGt1BUu6tl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}